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Subtype-Independent Immature Secretion and Subtype-Dependent Replication Deficiency of a Highly Frequent, Naturally Occurring Mutation of Human Hepatitis B Virus Core Antigen

The most frequent mutation of the human hepatitis B virus (HBV) core antigen occurs at amino acid 97. Recently, a phenylalanine (F)-to-leucine (L) mutation at this position (mutant F97L) in HBV surface antigen subtype ayw has been shown to result in an immature secretion phenotype, which is characte...

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Vydáno v:J Virol
Hlavní autoři: Yuan, Thomas Ta-Tung, Tai, Pei-Ching, Shih, Chiaho
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113064/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559327/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.10122-10128.1999
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