Transcriptional Up-Regulation of the Cyclin D2 Gene and Acquisition of New Cyclin-Dependent Kinase Partners in Human T-Cell Leukemia Virus Type 1-Infected Cells

Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent for adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis. Tax(1) is a 40-kDa phosphoprotein, predominantly localized in the nucleus of the host cell, which functions to transactivate both...

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Detalhes bibliográficos
Main Authors: Santiago, Francisco, Clark, Elizabeth, Chong, Siewyen, Molina, Carlos, Mozafari, Fariba, Mahieux, Renaud, Fujii, Masahiro, Azimi, Nazli, Kashanchi, Fatah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113041/
https://ncbi.nlm.nih.gov/pubmed/10559304
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