Loss of G(1)/S Checkpoint in Human Immunodeficiency Virus Type 1-Infected Cells Is Associated with a Lack of Cyclin-Dependent Kinase Inhibitor p21/Waf1

Productive high-titer infection by human immunodeficiency virus type 1 (HIV-1) requires the activation of target cells. Infection of quiescent peripheral CD4 lymphocytes by HIV-1 results in incomplete, labile reverse transcripts and lack of viral progeny formation. An interplay between Tat and p53 h...

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Detalhes bibliográficos
Main Authors: Clark, Elizabeth, Santiago, Francisco, Deng, Longwen, Chong, Siew yen, de la Fuente, Cynthia, Wang, Lai, Fu, Peng, Stein, Dana, Denny, Thomas, Lanka, Venkata, Mozafari, Fariba, Okamoto, Takashi, Kashanchi, Fatah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110856/
https://ncbi.nlm.nih.gov/pubmed/10799578
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