Binding of Polyomavirus Small T Antigen to Protein Phosphatase 2A Is Required for Elimination of p27 and Support of S-Phase Induction in Concert with Large T Antigen

Although polyomavirus large T antigen readily transactivates S-phase-specific enzymes in serum-starved Swiss 3T3 mouse fibroblasts, it is incapable by itself to efficiently drive such cells into S phase. We describe here that this inability correlates with a weak proficiency of the viral protein to...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Schüchner, Stefan, Wintersberger, Erhard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112961/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10516035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.11.9266-9273.1999
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