Amino Acids of Conserved Kinase Motifs of Cytomegalovirus Protein UL97 Are Essential for Autophosphorylation

Thirteen point mutations targeting predicted domains conserved in homologous protein kinases were introduced into the UL97 coding region of the human cytomegalovirus. All mutagenized proteins were expressed in cells infected with recombinant vaccinia viruses (rVV). Several mutations drastically redu...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Michel, Detlef, Kramer, Silke, Höhn, Simone, Schaarschmidt, Peter, Wunderlich, Kirsten, Mertens, Thomas
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Replication
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112917/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8898-8901.1999
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