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Investigating local conformations of double-stranded DNA by low-energy circular dichroism of pyrrolo-cytosine

Local base stacking and conformational mobility play a major role in the structure and function of nucleic acids. We have recently shown that the low-energy CD spectrum of 2-aminopurine (2-AP), i.e., the CD spectral region above 300 nm, can be used to monitor conformational changes in polynucleotide...

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Autors principals: Johnson, Neil P., Baase, Walter A., von Hippel, Peter H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1129127/
https://ncbi.nlm.nih.gov/pubmed/15883388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502359102
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