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Isolation and characterization of a retinal pigment epithelial cell fluorophore: An all-trans-retinal dimer conjugate

Several lines of investigation suggest that the nondegradable fluorophores that accumulate as lipofuscin in retinal pigment epithelium (RPE) cells contribute to the etiology of macular degeneration. Despite evidence that much of this fluorescent material may originate as inadvertent products of the...

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Bibliographic Details
Main Authors: Fishkin, Nathan E., Sparrow, Janet R., Allikmets, Rando, Nakanishi, Koji
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1129110/
https://ncbi.nlm.nih.gov/pubmed/15870200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501266102
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