Altered Virulence of Vaccine Strains of Measles Virus after Prolonged Replication in Human Tissue

To understand the molecular determinants of measles virus (MV) virulence, we have used the SCID-hu thymus/liver xenograft model (SCID-hu thy/liv) in which in vivo MV virulence phenotypes are faithfully duplicated. Stromal epithelial and monocytic cells are infected by MV in thymus implants, and viru...

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Pubblicato in:	J Virol
Autori principali:	Valsamakis, Alexandra, Auwaerter, Paul G., Rima, Bert K., Kaneshima, Hideto, Griffin, Diane E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Vaccines and Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112900/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8791-8797.1999
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