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Altered Virulence of Vaccine Strains of Measles Virus after Prolonged Replication in Human Tissue

To understand the molecular determinants of measles virus (MV) virulence, we have used the SCID-hu thymus/liver xenograft model (SCID-hu thy/liv) in which in vivo MV virulence phenotypes are faithfully duplicated. Stromal epithelial and monocytic cells are infected by MV in thymus implants, and viru...

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書誌詳細
出版年:J Virol
主要な著者: Valsamakis, Alexandra, Auwaerter, Paul G., Rima, Bert K., Kaneshima, Hideto, Griffin, Diane E.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482633/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8791-8797.1999
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