Mosaic Structure of the Human Immunodeficiency Virus Type 1 Genome Infecting Lymphoid Cells and the Brain: Evidence for Frequent In Vivo Recombination Events in the Evolution of Regional Populations

In addition to immunodeficiency, human immunodeficiency virus type 1 (HIV-1) can cause cognitive impairment and dementia through direct infection of the brain. To investigate the adaptive process and timing of HIV-1 entry into the central nervous system, we carried out an extensive genetic character...

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Autors principals: Morris, A., Marsden, M., Halcrow, K., Hughes, E. S., Brettle, R. P., Bell, J. E., Simmonds, P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Recombination and Evolution
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC112893/
https://ncbi.nlm.nih.gov/pubmed/10482626
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