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Mosaic Structure of the Human Immunodeficiency Virus Type 1 Genome Infecting Lymphoid Cells and the Brain: Evidence for Frequent In Vivo Recombination Events in the Evolution of Regional Populations

In addition to immunodeficiency, human immunodeficiency virus type 1 (HIV-1) can cause cognitive impairment and dementia through direct infection of the brain. To investigate the adaptive process and timing of HIV-1 entry into the central nervous system, we carried out an extensive genetic character...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Morris, A., Marsden, M., Halcrow, K., Hughes, E. S., Brettle, R. P., Bell, J. E., Simmonds, P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112893/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482626/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8720-8731.1999
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