Mosaic Structure of the Human Immunodeficiency Virus Type 1 Genome Infecting Lymphoid Cells and the Brain: Evidence for Frequent In Vivo Recombination Events in the Evolution of Regional Populations

In addition to immunodeficiency, human immunodeficiency virus type 1 (HIV-1) can cause cognitive impairment and dementia through direct infection of the brain. To investigate the adaptive process and timing of HIV-1 entry into the central nervous system, we carried out an extensive genetic character...

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Publié dans:	J Virol
Auteurs principaux:	Morris, A., Marsden, M., Halcrow, K., Hughes, E. S., Brettle, R. P., Bell, J. E., Simmonds, P.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1999
Sujets:	Recombination and Evolution
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112893/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482626/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8720-8731.1999
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