Postinoculation PMPA Treatment, but Not Preinoculation Immunomodulatory Therapy, Protects against Development of Acute Disease Induced by the Unique Simian Immunodeficiency Virus SIVsmmPBj

The fatal disease induced by SIVsmmPBj4 clinically resembles endotoxic shock, with the development of severe gastrointestinal disease. While the exact mechanism of disease induction has not been fully elucidated, aspects of virus biology suggest that immune activation contributes to pathogenesis. Th...

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Detalhes bibliográficos
Main Authors: Hodge, Shekema, de Rosayro, Juliette, Glenn, Amanda, Ojukwu, Ifeoma C., Dewhurst, Stephen, McClure, Harold M., Bischofberger, Norbert, Anderson, Daniel C., Klumpp, Sherry A., Novembre, Francis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112883/
https://ncbi.nlm.nih.gov/pubmed/10482616
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