Inhibition of Human Immunodeficiency Virus Type 1 Infectivity by the gp41 Core: Role of a Conserved Hydrophobic Cavity in Membrane Fusion

The gp41 envelope protein of human immunodeficiency virus type 1 (HIV-1) contains an α-helical core structure responsible for mediating membrane fusion during viral entry. Recent studies suggest that a conserved hydrophobic cavity in the coiled coil of this core plays a distinctive structural role i...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Ji, Hong, Shu, Wei, Burling, F. Temple, Jiang, Shibo, Lu, Min
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Structure and Assembly
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112878/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8578-8586.1999
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