Inhibition of Human Immunodeficiency Virus Type 1 Infectivity by the gp41 Core: Role of a Conserved Hydrophobic Cavity in Membrane Fusion
The gp41 envelope protein of human immunodeficiency virus type 1 (HIV-1) contains an α-helical core structure responsible for mediating membrane fusion during viral entry. Recent studies suggest that a conserved hydrophobic cavity in the coiled coil of this core plays a distinctive structural role i...
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| Publicado en: | J Virol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112878/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8578-8586.1999 |
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