Protection by Live, Attenuated Simian Immunodeficiency Virus against Heterologous Challenge

We examined the ability of a live, attenuated deletion mutant of simian immunodeficiency virus (SIV), SIVmac239Δ3, which is missing nef and vpr genes, to protect against challenge by heterologous strains SHIV89.6p and SIVsmE660. SHIV89.6p is a pathogenic, recombinant SIV in which the envelope gene h...

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Pubblicato in:	J Virol
Autori principali:	Wyand, Michael S., Manson, Kelledy, Montefiori, David C., Lifson, Jeffrey D., Johnson, R. Paul, Desrosiers, Ronald C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482586/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8356-8363.1999
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