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Adaptation of a CCR5-Using, Primary Human Immunodeficiency Virus Type 1 Isolate for CD4-Independent Replication

The gp120 envelope glycoprotein of the human immunodeficiency virus type 1 (HIV-1) promotes virus entry by sequentially binding CD4 and chemokine receptors on the target cell. Primary, clinical HIV-1 isolates require interaction with CD4 to allow gp120 to bind the CCR5 chemokine receptor efficiently...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Kolchinsky, Peter, Mirzabekov, Tajib, Farzan, Michael, Kiprilov, Enko, Cayabyab, Mark, Mooney, Larissa J., Choe, Hyeryun, Sodroski, Joseph
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112828/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482561/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8120-8126.1999
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