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Mutation of Neuraminidase Cysteine Residues Yields Temperature-Sensitive Influenza Viruses

The influenza virus neuraminidase (NA) is a tetrameric, virus surface glycoprotein possessing receptor-destroying activity. This enzyme facilitates viral release and is a target of anti-influenza virus drugs. The NA structure has been extensively studied, and the locations of disulfide bonds within...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Basler, Christopher F., García-Sastre, Adolfo, Palese, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112825/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482558/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8095-8103.1999
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