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Human MxA Protein Protects Mice Lacking a Functional Alpha/Beta Interferon System against La Crosse Virus and Other Lethal Viral Infections

The human MxA protein is part of the antiviral state induced by alpha/beta interferon (IFN-α/β). MxA inhibits the multiplication of several RNA viruses in cell culture. However, its antiviral potential in vivo has not yet been fully explored. We have generated MxA-transgenic mice that lack a functio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hefti, Hans Peter, Frese, Michael, Landis, Heinrich, Di Paolo, Claudio, Aguzzi, Adriano, Haller, Otto, Pavlovic, Jovan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 1999
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC112784/
https://ncbi.nlm.nih.gov/pubmed/10400797
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