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Structure of Adenovirus Complexed with Its Internalization Receptor, α(v)β5 Integrin

The three-dimensional structure of soluble recombinant integrin α(v)β5 bound to human adenovirus types 2 and 12 (Ad2 and -12) has been determined at ∼21-Å resolution by cryoelectron microscopy (cryo-EM). The α(v)β5 integrin is known to promote Ad cell entry. Cryo-EM has shown that the integrin-bindi...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Chiu, Charles Y., Mathias, Patricia, Nemerow, Glen R., Stewart, Phoebe L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112761/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10400774/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.8.6759-6768.1999
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