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Structure of Adenovirus Complexed with Its Internalization Receptor, α(v)β5 Integrin

The three-dimensional structure of soluble recombinant integrin α(v)β5 bound to human adenovirus types 2 and 12 (Ad2 and -12) has been determined at ∼21-Å resolution by cryoelectron microscopy (cryo-EM). The α(v)β5 integrin is known to promote Ad cell entry. Cryo-EM has shown that the integrin-bindi...

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Bibliografiske detaljer
Main Authors: Chiu, Charles Y., Mathias, Patricia, Nemerow, Glen R., Stewart, Phoebe L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC112761/
https://ncbi.nlm.nih.gov/pubmed/10400774
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