Integrin αvβ1 Is an Adenovirus Coreceptor

The human embryonic kidney (HEK293) cell line, commonly used for recombinant adenovirus (Ad) propagation, does not express the Ad coreceptor αvβ3 or αvβ5 integrins, yet these cells are efficiently infected by Ad vectors. Here we demonstrate that Ad binds to HEK293 cells via the fiber receptor CAR an...

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Autors principals: Li, Erguang, Brown, Swati L., Stupack, Dwayne G., Puente, Xose S., Cheresh, David A., Nemerow, Glen R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114949/
https://ncbi.nlm.nih.gov/pubmed/11333925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.5405-5409.2001
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