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Integrin αvβ1 Is an Adenovirus Coreceptor

The human embryonic kidney (HEK293) cell line, commonly used for recombinant adenovirus (Ad) propagation, does not express the Ad coreceptor αvβ3 or αvβ5 integrins, yet these cells are efficiently infected by Ad vectors. Here we demonstrate that Ad binds to HEK293 cells via the fiber receptor CAR an...

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書誌詳細
主要な著者: Li, Erguang, Brown, Swati L., Stupack, Dwayne G., Puente, Xose S., Cheresh, David A., Nemerow, Glen R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC114949/
https://ncbi.nlm.nih.gov/pubmed/11333925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.5405-5409.2001
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