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Escape of Human Cytomegalovirus from HLA-DR-Restricted CD4(+) T-Cell Response Is Mediated by Repression of Gamma Interferon-Induced Class II Transactivator Expression

Human cytomegalovirus (HCMV), a betaherpesvirus, is a pathogen which escapes immune recognition through various mechanisms. In this paper, we show that HCMV down regulates gamma interferon (IFN-γ)-induced HLA-DR expression in U373 MG astrocytoma cells due to a defect downstream of STAT1 phosphorylat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Le Roy, Emmanuelle, Mühlethaler-Mottet, Annick, Davrinche, Christian, Mach, Bernard, Davignon, Jean-Luc
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC112742/
https://ncbi.nlm.nih.gov/pubmed/10400755
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