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Escape of Human Cytomegalovirus from HLA-DR-Restricted CD4(+) T-Cell Response Is Mediated by Repression of Gamma Interferon-Induced Class II Transactivator Expression
Human cytomegalovirus (HCMV), a betaherpesvirus, is a pathogen which escapes immune recognition through various mechanisms. In this paper, we show that HCMV down regulates gamma interferon (IFN-γ)-induced HLA-DR expression in U373 MG astrocytoma cells due to a defect downstream of STAT1 phosphorylat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC112742/ https://ncbi.nlm.nih.gov/pubmed/10400755 |
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