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Human Immunodeficiency Virus Type 1 Strains R5 and X4 Induce Different Pathogenic Effects in hu-PBL-SCID Mice, Depending on the State of Activation/Differentiation of Human Target Cells at the Time of Primary Infection

In a previous study, we had found that the extent of T-cell dysfunctions induced by a T-tropic strain of human immunodeficiency virus type 1 (HIV-1) in SCID mice reconstituted with human peripheral blood lymphocytes (hu-PBLs) (hu-PBL-SCID mice) was related to the in vivo state of activation of the h...

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Autors principals: Fais, Stefano, Lapenta, Caterina, Santini, Stefano M., Spada, Massimo, Parlato, Stefania, Logozzi, Mariantonia, Rizza, Paola, Belardelli, Filippo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC112726/
https://ncbi.nlm.nih.gov/pubmed/10400739
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