Species-Independent Inhibition of Abnormal Prion Protein (PrP) Formation by a Peptide Containing a Conserved PrP Sequence

Conversion of the normal protease-sensitive prion protein (PrP) to its abnormal protease-resistant isoform (PrP-res) is a major feature of the pathogenesis associated with transmissible spongiform encephalopathy (TSE) diseases. In previous experiments, PrP conversion was inhibited by a peptide compo...

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הוצא לאור ב:	J Virol
Principais autores:	Chabry, Joëlle, Priola, Suzette A., Wehrly, Kathy, Nishio, Jane, Hope, James, Chesebro, Bruce
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 1999
נושאים:	Pathogenesis and Immunity
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112701/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10400714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.8.6245-6250.1999
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