Use of Major Histocompatibility Complex Class I/Peptide/β2M Tetramers To Quantitate CD8(+) Cytotoxic T Lymphocytes Specific for Dominant and Nondominant Viral Epitopes in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys
To evaluate the impact of the diversity of antigen recognition by T lymphocytes on disease pathogenesis, we must be able to identify and analyze simultaneously cytotoxic T-lymphocyte (CTL) responses specific for multiple viral epitopes. Many of the studies of the role of CD8(+) CTLs in AIDS pathogen...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112603/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364294/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.5466-5472.1999 |
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