Use of Major Histocompatibility Complex Class I/Peptide/β2M Tetramers To Quantitate CD8(+) Cytotoxic T Lymphocytes Specific for Dominant and Nondominant Viral Epitopes in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys

To evaluate the impact of the diversity of antigen recognition by T lymphocytes on disease pathogenesis, we must be able to identify and analyze simultaneously cytotoxic T-lymphocyte (CTL) responses specific for multiple viral epitopes. Many of the studies of the role of CD8(+) CTLs in AIDS pathogen...

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Main Authors: Egan, Michael A., Kuroda, Marcelo J., Voss, Gerald, Schmitz, Jörn E., Charini, William A., Lord, Carol I., Forman, Meryl A., Letvin, Norman L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112603/
https://ncbi.nlm.nih.gov/pubmed/10364294
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