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Use of Major Histocompatibility Complex Class I/Peptide/β2M Tetramers To Quantitate CD8(+) Cytotoxic T Lymphocytes Specific for Dominant and Nondominant Viral Epitopes in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys
To evaluate the impact of the diversity of antigen recognition by T lymphocytes on disease pathogenesis, we must be able to identify and analyze simultaneously cytotoxic T-lymphocyte (CTL) responses specific for multiple viral epitopes. Many of the studies of the role of CD8(+) CTLs in AIDS pathogen...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Microbiology
1999
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC112603/ https://ncbi.nlm.nih.gov/pubmed/10364294 |
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