Use of Major Histocompatibility Complex Class I/Peptide/β2M Tetramers To Quantitate CD8(+) Cytotoxic T Lymphocytes Specific for Dominant and Nondominant Viral Epitopes in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys

To evaluate the impact of the diversity of antigen recognition by T lymphocytes on disease pathogenesis, we must be able to identify and analyze simultaneously cytotoxic T-lymphocyte (CTL) responses specific for multiple viral epitopes. Many of the studies of the role of CD8(+) CTLs in AIDS pathogen...

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Pubblicato in:	J Virol
Autori principali:	Egan, Michael A., Kuroda, Marcelo J., Voss, Gerald, Schmitz, Jörn E., Charini, William A., Lord, Carol I., Forman, Meryl A., Letvin, Norman L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112603/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364294/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.5466-5472.1999
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