Induction of Human Papillomavirus-Specific CD4(+) and CD8(+) Lymphocytes by E7-Pulsed Autologous Dendritic Cells in Patients with Human Papillomavirus Type 16- and 18-Positive Cervical Cancer

Human papillomavirus (HPV) type 16 (HPV 16) and HPV type 18 (HPV 18) are implicated in the induction and progression of the majority of cervical cancers. Since the E6 and E7 oncoproteins of these viruses are expressed in these lesions, such proteins might be potential tumor-specific targets for immu...

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Bibliographic Details
Main Authors: Santin, Alessandro D., Hermonat, Paul L., Ravaggi, Antonella, Chiriva-Internati, Maurizio, Zhan, Dejin, Pecorelli, Sergio, Parham, Groesbeck P., Cannon, Martin J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC112596/
https://ncbi.nlm.nih.gov/pubmed/10364287
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