Combinatorial Screening and Intracellular Antiviral Activity of Hairpin Ribozymes Directed against Hepatitis B Virus
A combinatorial screening method has been used to identify hairpin ribozymes that inhibit hepatitis B virus (HBV) replication in transfected human hepatocellular carcinoma (HCC) cells. A hairpin ribozyme library (5 × 10(5) variants) containing a randomized substrate-binding domain was used to identi...
محفوظ في:
| الحاوية / القاعدة: | J Virol |
|---|---|
| المؤلفون الرئيسيون: | , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
1999
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364285/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.5381-5387.1999 |
| الوسوم: |
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