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Glycoprotein D or J Delivered in trans Blocks Apoptosis in SK-N-SH Cells Induced by a Herpes Simplex Virus 1 Mutant Lacking Intact Genes Expressing Both Glycoproteins

We have made two stocks of a herpes simplex virus 1 mutant lacking intact U(S)5 and U(S)6 open reading frames encoding glycoproteins J (gJ) and D (gD), respectively. The stock designated gD(−/+), made in cells carrying U(S)6 and expressing gD, was capable of productively infecting cells, whereas the...

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Udgivet i:J Virol
Principais autores: Zhou, Guoying, Galvan, Veronica, Campadelli-Fiume, Gabriella, Roizman, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112461/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11090178/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.24.11782-11791.2000
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