Integrase-LexA Fusion Proteins Incorporated into Human Immunodeficiency Virus Type 1 That Contains a Catalytically Inactive Integrase Gene Are Functional To Mediate Integration

Purified fusion proteins made up of a retroviral integrase and a sequence-specific DNA-binding protein have been tested in in vitro assays for their ability to direct integration into specific target sites. To determine whether these fusion proteins can be incorporated into human immunodeficiency vi...

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Bibliographic Details
Main Authors: Holmes-Son, Michelle L., Chow, Samson A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Gene Therapy
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC112435/
https://ncbi.nlm.nih.gov/pubmed/11090152
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