Identification of Notch1 as a Frequent Target for Provirus Insertional Mutagenesis in T-Cell Lymphomas Induced by Leukemogenic Mutants of Mouse Mammary Tumor Virus

In contrast to wild-type mouse mammary tumor virus (MMTV), the MMTV mutants with specific deletions in the U3 region of their long terminal repeats cause T-cell lymphomas. In 30% of T-cell lymphomas arising in BALB/c mice infected with MLA-MMTV, a leukemogenic MMTV mutant, we have found that MMTV pr...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Yanagawa, Shin-ichi, Lee, Jong-Seo, Kakimi, Kazuhiro, Matsuda, Yukihiro, Honjo, Tasuku, Ishimoto, Akinori
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Transformation and Oncogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112415/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11000255/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.20.9786-9791.2000
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