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Diminished Primary and Secondary Influenza Virus-Specific CD8(+) T-Cell Responses in CD4-Depleted Ig(−/−) Mice
Optimal expansion of influenza virus nucleoprotein (D(b)NP(366))-specific CD8(+) T cells following respiratory challenge of naive Ig(−/−) μMT mice was found to require CD4(+) T-cell help, and this effect was also observed in primed animals. Absence of the CD4(+) population was consistently correlate...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC112411/ https://ncbi.nlm.nih.gov/pubmed/11000251 |
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