Activation of Interferon Regulatory Factor 3 Is Inhibited by the Influenza A Virus NS1 Protein
We present a novel mechanism by which viruses may inhibit the alpha/beta interferon (IFN-α/β) cascade. The double-stranded RNA (dsRNA) binding protein NS1 of influenza virus is shown to prevent the potent antiviral interferon response by inhibiting the activation of interferon regulatory factor 3 (I...
محفوظ في:
| الحاوية / القاعدة: | J Virol |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
2000
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112330/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10933707/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.17.7989-7996.2000 |
| الوسوم: |
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