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Structural and Kinetic Analyses of the Protease from an Amprenavir-Resistant Human Immunodeficiency Virus Type 1 Mutant Rendered Resistant to Saquinavir and Resensitized to Amprenavir

Recent drug regimens have had much success in the treatment of human immunodeficiency virus (HIV)-infected individuals; however, the incidence of resistance to such drugs has become a problem that is likely to increase in importance with long-term therapy of this chronic illness. An analysis and und...

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Bibliografiska uppgifter
Huvudupphovsmän: Markland, W., Rao, B. G., Parsons, J. D., Black, J., Zuchowski, L., Tisdale, M., Tung, R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC112285/
https://ncbi.nlm.nih.gov/pubmed/10906218
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