Structural and Kinetic Analyses of the Protease from an Amprenavir-Resistant Human Immunodeficiency Virus Type 1 Mutant Rendered Resistant to Saquinavir and Resensitized to Amprenavir

Recent drug regimens have had much success in the treatment of human immunodeficiency virus (HIV)-infected individuals; however, the incidence of resistance to such drugs has become a problem that is likely to increase in importance with long-term therapy of this chronic illness. An analysis and und...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Markland, W., Rao, B. G., Parsons, J. D., Black, J., Zuchowski, L., Tisdale, M., Tung, R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10906218/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.16.7636-7641.2000
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