Structural Determinants of Murine Leukemia Virus Reverse Transcriptase That Affect the Frequency of Template Switching

Retroviral reverse transcriptases (RTs) frequently switch templates within the same RNA or between copackaged viral RNAs to generate mutations and recombination. To identify structural elements of murine leukemia virus RT important for template switching, we developed an in vivo assay in which RT te...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Svarovskaia, Evguenia S., Delviks, Krista A., Hwang, Carey K., Pathak, Vinay K.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Replication
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112237/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10888659/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.15.7171-7178.2000
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