Quantitation of CD8(+) T-Lymphocyte Responses to Multiple Epitopes from Simian Virus 40 (SV40) Large T Antigen in C57BL/6 Mice Immunized with SV40, SV40 T-Antigen-Transformed Cells, or Vaccinia Virus Recombinants Expressing Full-Length T Antigen or Epitope Minigenes

The cytotoxic T-lymphocyte response to wild-type simian virus 40 large tumor antigen (Tag) in C57BL/6 (H2(b)) mice is directed against three H2-D(b)-restricted epitopes, I, II/III, and V, and one H2-K(b)-restricted epitope, IV. Epitopes I, II/III, and IV are immunodominant, while epitope V is immuno...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Mylin, Lawrence M., Schell, Todd D., Roberts, Debra, Epler, Melanie, Boesteanu, Alina, Collins, Edward J., Frelinger, Jeffrey A., Joyce, Sebastian, Tevethia, Satvir S.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Vaccines and Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112209/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10888631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.15.6922-6934.2000
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