Differences in the Ability of Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) and HTLV-2 Tax To Inhibit p53 Function

We have analyzed the functional activity of the p53 tumor suppressor in human T-cell lymphotropic virus type 2 (HTLV-2)-transformed cells. Abundant levels of the p53 protein were detected in both HTLV-2A and -2B virus-infected cell lines. The p53 was functionally inactive, however, both in transient...

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Détails bibliographiques
Auteurs principaux: Mahieux, Renaud, Pise-Masison, Cynthia A., Lambert, Paul F., Nicot, Christophe, De Marchis, Laura, Gessain, Antoine, Green, Patrick, Hall, William, Brady, John N.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
Sujets:
Transformation and Oncogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC112204/
https://ncbi.nlm.nih.gov/pubmed/10888626
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