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Differences in the Ability of Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) and HTLV-2 Tax To Inhibit p53 Function

We have analyzed the functional activity of the p53 tumor suppressor in human T-cell lymphotropic virus type 2 (HTLV-2)-transformed cells. Abundant levels of the p53 protein were detected in both HTLV-2A and -2B virus-infected cell lines. The p53 was functionally inactive, however, both in transient...

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Sparad:
I publikationen:J Virol
Huvudupphov: Mahieux, Renaud, Pise-Masison, Cynthia A., Lambert, Paul F., Nicot, Christophe, De Marchis, Laura, Gessain, Antoine, Green, Patrick, Hall, William, Brady, John N.
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 2000
Ämnen:
Transformation and Oncogenesis
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112204/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10888626/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.15.6866-6874.2000
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