Gamma Interferon Impedes the Establishment of Herpes Simplex Virus Type 1 Latent Infection but Has No Impact on Its Maintenance or Reactivation in Mice

Murine models of gamma interferon (IFN-γ) deficiency demonstrate the role of this cytokine in attenuating acute herpes simplex virus (HSV) disease; however, the effect of IFN-γ on the establishment and maintenance of neuronal latency and viral reactivation is not known. Using the IFN-γ knockout (GKO...

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Vydáno v:	J Virol
Hlavní autoři:	Lekstrom-Himes, Julie A., LeBlanc, Rona A., Pesnicak, Lesley, Godleski, Matthew, Straus, Stephen E.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2000
Témata:	Pathogenesis and Immunity
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112181/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10864685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.14.6680-6683.2000
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