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Human Papillomavirus Type 16 E7 Oncoprotein Represses Transcription of Human Fibronectin

The E7 oncoprotein encoded by human papillomavirus (HPV) type 16 repressed the transcription of fibronectin, a key component of the extracellular matrix. This repression, detected in several HPV-positive nontumorigenic and tumorigenic cell lines, was abolished when the Cys-X-X-Cys repeats in E7 were...

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Bibliographic Details
Main Authors: Rey, Osvaldo, Lee, Sora, Park, No-Hee
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC112019/
https://ncbi.nlm.nih.gov/pubmed/10775635
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