Pathogenesis of Herpes Simplex Virus-Induced Ocular Immunoinflammatory Lesions in B-Cell-Deficient Mice

The role of B cells and humoral immunity in herpes simplex virus (HSV) ocular infections was studied in immunoglobulin μ chain gene-targeted B-cell-deficient mice (μK/O). At doses of virus well tolerated by immunocompetent mice, heightened susceptibility of μK/O mice to herpetic encephalitis as well...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Deshpande, Shilpa P., Zheng, Mei, Daheshia, Massoud, Rouse, Barry T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111859/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10729125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.8.3517-3524.2000
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