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Assembly and Processing of Human Immunodeficiency Virus Gag Mutants Containing a Partial Replacement of the Matrix Domain by the Viral Protease Domain

We constructed human immunodeficiency virus (HIV) mutants by replacing the matrix domain with sequences encoding the viral protease or p6* and protease. The chimeras retaining matrix myristylation and processing signals underwent efficient autoprocessing with severely defective particle budding. The...

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Detalhes bibliográficos
Main Authors: Wang, Chin-Tien, Chou, Yen-Chiou, Chiang, Chien-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111845/
https://ncbi.nlm.nih.gov/pubmed/10708461
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