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Gag-Pol Transframe Domain p6* Is Essential for HIV-1 Protease-Mediated Virus Maturation
HIV-1 protease (PR) is encoded by pol, which is initially translated as a Pr160(gag-pol) polyprotein by a ribosomal frameshift event. Within Gag-Pol, truncated p6gag is replaced by a transframe domain (referred to as p6* or p6pol) located directly upstream of PR. p6* has been proposed as playing a r...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4451514/ https://ncbi.nlm.nih.gov/pubmed/26030443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127974 |
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