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Human Immunodeficiency Virus Type 1 Vpr Induces Apoptosis through Caspase Activation

Human immunodeficiency virus type 1 (HIV-1) Vpr is a 96-amino-acid protein that is found associated with the HIV-1 virion. Vpr induces cell cycle arrest at the G(2)/M phase of the cell cycle, and this arrest is followed by apoptosis. We examined the mechanism of Vpr-induced apoptosis and found that...

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Autori principali: Stewart, Sheila A., Poon, Betty, Song, Joo Y., Chen, Irvin S. Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC111809/
https://ncbi.nlm.nih.gov/pubmed/10708425
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