Human Immunodeficiency Virus Type 1 Vpr Induces Apoptosis through Caspase Activation

Human immunodeficiency virus type 1 (HIV-1) Vpr is a 96-amino-acid protein that is found associated with the HIV-1 virion. Vpr induces cell cycle arrest at the G(2)/M phase of the cell cycle, and this arrest is followed by apoptosis. We examined the mechanism of Vpr-induced apoptosis and found that...

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Опубликовано в::	J Virol
Главные авторы:	Stewart, Sheila A., Poon, Betty, Song, Joo Y., Chen, Irvin S. Y.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2000
Предметы:	Pathogenesis and Immunity
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111809/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10708425/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.7.3105-3111.2000
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